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אגנטק מזמינה אתכם לשמוע את הרצאתו ד"ר מתיאס מולנר מחברת NanoTemper Technologies במהלך תערוכת ישראנליטיקה 2018

MicroScale Thermophoresis and Nano Differential Scanning Fluorimetry: Using Low-Volume Rapid Innovative Technologies to Accelerate Research in Protein Characterization, Binding Affinity and Stability
 
יום רביעי, 24,1, Hall B, בין השעות 15:50-16:10

ד"ר מולנר ייתארח בביתן אגנטק במהלך התערוכה וישמח לענות על שאלותיכם

MicroScale Thermophoresis and Nano Differential Scanning Fluorimetry: Using Low-Volume Rapid Innovative Technologies to Accelerate Research in Protein Characterization, Binding Affinity and Stability
 
By combining two breakthrough technologies, with user-centric design, scientists in basic and pharmaceutical research are able to get better results faster.
Using MicroScale Thermophoresis (MST) affinities for all kind of interactions are quantified in minutes using a few µl of sample. In addition, the unique properties of MST technology can help identify unique hits which are not detected by orthogonal methods and moreover can discriminate true hits from aggregating or denaturing compounds. Large compound libraries can be easily screened in a fully automated fashion with unprecedented speed to robustly detect true binding events while ruling out potential false positives.
 
Predicting biologics stability can be easily achieved using an advanced approach to nano Differential Scanning Fluorimetry (nanoDSF) specifically tailored for thermal and chemical unfolding characterization of proteins. This label-free technology requires only a fraction of sample and time compared to conventional methods, and can be easily integrated into virtually every step of the biologics development workflows. By using this combinatorial approach, we can robustly predict the long-term stability of biologics, streamlining the development process and consequently leading to a reduced time to market.