diathus

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Nanotemper Dianthus

Dianthus is a plate-based and microfluidics-free affinity screening platform

Measurements are in solution and mass-independent — ideal for succeeding at demanding screening campaigns.

It’s not surprising that the most important drug candidates and targets are super challenging when it comes to affinity screening. Immobilization-dependent SPR struggles with affinity screening campaigns for applications involving PROTAC binary and ternary complexes, fragment libraries, and intrinsically disordered proteins. These are precisely the applications where Dianthus excels.

 

Now with Spectral Shift and TRIC, two methods for measuring molecular interactions, Dianthus delivers high-quality data, has the sensitivity to detect more true binders, and requires less assay development to give you results from real-life samples.

 

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